PALO ALTO, Calif.--(BUSINESS WIRE)--Inscopix, Inc., a brain mapping platform company developing neurotechnologies to decode the brain for improved disease treatments, will display the latest product and research innovations around its miniature microscope-based neural circuitry technology at the 50th annual meeting of the Society for Neuroscience (SfN), to be held virtually November 8-11.
Showcasing new technologies that enable dual color imaging, neurotransmitter release and blood flow dynamics visualizations with Inscopix’s revolutionary platform for understanding the circuitry of the brain, these ground-breaking new technologies will help researchers gain deeper insights in neural circuit function and behavior that can ultimately lead to breakthrough discoveries and the development of novel, more precise therapeutics for neuropsychiatric, neurodegenerative diseases and brain-related injuries. Data will be shown on all three novel imaging capabilities at Inscopix’s scientific presentations at SfN.
New Imaging Technologies for Neuroscientists
Inscopix’s SfN virtual booth will highlight key innovations that expand the company’s product and applications portfolio.
- Dual Color Imaging - The nVue™ system, the most innovative Inscopix platform yet, enables simultaneous dual color imaging in freely behaving subjects, making it possible to investigate the interaction between two distinct brain signals in longitudinal studies.
- Blood Flow Imaging - For neurovascular coupling insights, the new application uses the nVue system and allows simultaneous imaging of neural activity and blood flow dynamics in cortical and deep brain regions.
- Neurotransmitter Imaging - The novel application enables visualization of genetically-encoded optical sensors of neurotransmitter activity with calcium dynamics.
In a significant step towards empowering the customer community, Inscopix is also introducing a new digital experience and learning platform named Inscopix iQ. Tailored to the individual customer’s research needs, Inscopix iQ is one central online platform integrating numerous scientific, technical and purchasing resources to nurture a multimodal scientific journey. Features built into the customer’s iQ account include a dashboard with account information, custom-built learning plans with engaging courses and an updated intuitive product webstore.
“We are excited to build on the commercial release earlier this year of our dual color brain imaging system, nVue. We have been amazed at how quickly nVue has been adopted by the circuit neuroscience research community, and at this SfN, we are releasing and showcasing new imaging applications enabled by nVue that take us beyond imaging of calcium activity,” said Kunal Ghosh, Ph.D., founder and CEO of Inscopix. “The ability to understand neurovascular coupling by imaging blood flow dynamics together with calcium activity, and the ability to study neurotransmitter release in conjunction with neuronal calcium activity, are applications relevant to researchers across the basic and translational neuroscience spectrum.”
Presentations Showcasing Leading Neuroscience Research
Three abstracts will be presented by Inscopix scientists, showcasing the above described applications enabled by the company’s brain mapping platforms, namely dual color, blood flow and neurotransmitter imaging. Inscopix will provide details of additional abstracts throughout the annual meeting via its corporate Twitter account @inscopix.
Presentations by Inscopix include:
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Imaging genetically encoded neurotransmitter sensors using head-mountable miniscopes
Presented by Kevin Zitelli, Ph.D.
Session P933: Optical Methods: Imaging Neural Activity and Behavioral Analysis
November 8th, 2021 from 1:00 PM to 2:00 PM CDT
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Measuring simultaneous neural activity and blood flow in awake freely behaving animals
Presented by Srishti Gulati, Ph.D.
Session P927: Optical Methodologies
November 8th, 2021 from 1:15 to 2:15 PM CDT
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Dual color imaging in freely-behaving rodents using a head-mountable one photon miniscope
Presented by Giorgio Rizzi
Session P928: Optical Methodology: Calcium Indicators and Related Methodologies
November 11th, 2021 from 10:00 to 11:00 AM CDT
“As Inscopix and its partners apply this powerful imaging approach to the development of better neurotherapeutics, these new imaging technologies allow us to gain new insights on brain circuitry, both at the neural and vascular level, and help us identify targeted therapies that are potentially both safer and more effective than currently available options," said David Gray, Ph.D., CSO of Inscopix.
Meeting attendees can visit Inscopix booth #928, or email sales@inscopix.com to schedule a conversation with a member of the company.
About nVue
nVue is Inscopix’s state-of-the-art miniscope-based solution for dual color imaging of two distinct cell populations in freely-behaving animals. With nVue, scientists at leading research institutions across the globe are pioneering new neuroscience discoveries and asking previously unanswerable questions on the involvement of neural circuits in health and disease. For more information, please visit: https://www.inscopix.com/nvue-system.
About Inscopix, Inc.
Inscopix is a brain mapping platform company focused on decoding the mind to better understand and address all neurological disorders. We are solving perhaps the greatest unmet need in humanity – understanding how the brain works – and leveraging that knowledge to develop effective neurological treatments. With almost 200 peer-reviewed publications validating our innovative brain circuitry mapping technology, Inscopix is empowering the neuroscience research community to advance science while bringing a new generation of transformational therapeutics to patients with difficult-to-treat brain disorders. Learn more at inscopix.com and follow us @inscopix.
