RESEARCH TRIANGLE PARK, N.C.--(BUSINESS WIRE)--Alessandra Vignola has joined Worldwide Clinical Trials (Worldwide), a global full-service contract research organization (CRO), as President of the Cardiovascular & Metabolic Business Unit. Vignola brings more than 30 years of extensive experience in the pharmaceutical and clinical research industry, enhancing the company's leadership in these critical therapeutic areas.
In this role, Vignola will oversee the Cardiovascular & Metabolic Business Unit, leading Worldwide’s therapeutically-focused team and partnering with sponsors to advance new medications through clinical development while driving business growth for Worldwide. Her appointment comes at a pivotal time for the cardiovascular and metabolic sectors, which are undergoing rapid advancements, particularly in the areas of diabetes and obesity, as well as across all cardiovascular-kidney-metabolic diseases, including metabolic dysfunction-associated steatohepatitis (MASH), metabolic dysfunction-associated steatotic liver disease (MASLD), and other acute and chronic liver diseases.
The escalating obesity epidemic is contributing to a surge in cardiovascular and metabolic comorbidities, including diabetes, liver disease, and other serious health conditions. As these interconnected health challenges become more prevalent, the need for effective treatment options is urgent. Research has expanded into various therapeutic approaches, including promising medications like GLP-1 (glucagon-like peptide-1) receptor agonists, initially developed for type 2 diabetes but now being explored for broader applications such as cardiovascular disease and obesity management. The growing focus on addressing obesity and its related conditions underscores the critical need for expert leadership in clinical research – an area in which Vignola's background is invaluable for sponsors with investigational agents.
"Alessandra's deep understanding of the cardiovascular and metabolic markets, combined with her proven track record of leading successful clinical programs, makes her an exceptional addition to our team," said Dave Bowser, Chief Operating Officer at Worldwide Clinical Trials. "Her expertise in navigating the complexities of these therapeutic areas, especially with the evolving landscape due to GLP-1 medications on the market, positions Worldwide to remain at the forefront of advancements and continue delivering innovative and high-quality services as we partner with our customers.”
“Today’s cardiovascular and metabolic markets are marked by significant challenges and opportunities. Cardiovascular diseases remain the leading cause of mortality worldwide, while metabolic disorders, including diabetes and obesity, are increasing at an alarming rate,” said Vignola. “The way Worldwide has partnered with its customers for nearly 40 years and the expert teams it has in place are impressive. I’m happy to join this team and drive more advancements in these areas for patients around the world.”
Vignola’s career began at Bristol-Myers Squibb (BMS), where she developed a strong foundation in the pharmaceutical sector. She then spent a decade at Pfizer, contributing to pivotal clinical research initiatives. Her 15-year tenure at PPD further solidified her expertise across various therapeutic areas, including oncology, hematology, cardiovascular, metabolic, gastrointestinal, liver, and immunology. Most recently, Vignola spent three years at Thermo Fisher Scientific, where she was instrumental in driving clinical trial strategies and ensuring operational excellence.
For more information on Worldwide’s experience and capabilities in the cardiovascular and metabolic therapeutic areas, visit www.Worldwide.com.
About Worldwide Clinical Trials
Worldwide Clinical Trials (Worldwide) is a full-service global contract research organization (CRO) that works in partnership with biotechnology and pharmaceutical companies to create customized solutions that advance new medications – from discovery to reality. Worldwide’s capabilities include bioanalytical laboratory services, Phase I-IV clinical trials, and post-approval and real-world evidence studies – all powered by an accessible team of clinicians, scientists, and researchers who bring first-hand expertise and a collaborative, personalized approach to each clinical program. Worldwide is therapeutically focused on neuroscience, oncology, rare diseases, and cardiometabolic and inflammatory disease. Its global footprint spans nearly 60 countries with more than 3,500 team members. For more information, visit www.worldwide.com.
