DUBLIN--(BUSINESS WIRE)--The "Opioid Induced Constipation Drugs Market Size, Market Share, Application Analysis, Regional Outlook, Growth Trends, Key Players, Competitive Strategies and Forecasts, 2022 to 2030" report has been added to ResearchAndMarkets.com's offering.
The global opioid induced constipation drugs market is rising at a significant pace, projected to rise at a CAGR of 4.7% during the estimated period from 2022 to 2030.
Companies Mentioned
- AstraZeneca plc
- Cubist Pharmaceuticals (Adolor Corporation)
- Daiichi Sankyo Co. Ltd.
- Ironwood Pharmaceuticals Inc.
- Pfizer Inc.
- Progenics Pharmaceuticals Inc.
- Salix Pharmaceuticals Ltd.
- Shionogo & Co. Ltd.
- Sucampo Pharmaceuticals Inc.
- Synergy Pharmaceuticals Inc
The mechanism of action of opioid analgesics through binding to the mu, delta, and kappa receptors present in the brain by crossing the blood-brain barrier and giving the desired analgesic effect to treat non-cancer pain. In addition, the opioids bind to the mu receptors present in the gastrointestinal tract, which result in a contraction of the smooth muscles and alter the peristaltic movement causing constipation.
Usually, the patients opt for over the counter osmotic laxatives and stimulant cathartics, which have been beneficial in providing relief from constipation in patients taking opioid analgesics for 3-4 weeks. In patients seeking palliative care, doctors prescribe mu-receptor antagonists and prostaglandin derivatives to cure opioid induced constipation.
In the present scenario, prescribed drugs are dominating the market on account of an increasing number of patients showing resistance to over-the-counter laxatives and cathartics. Moreover, opioid analgesics binds to the mu receptors of the gastrointestinal tract causing severe contraction of smooth muscles, altering the peristaltic activity of the gut motility, thus leading to chronic constipation.
Physicians usually prescribe branded drugs such as methylnaltrexone bromide and naloxegol (mu-receptor antagonists) and prostaglandin derivatives such as lubiprostone to gain immediate relief from constipation by increasing fluid retention and stool softening. Over the counter (OTC) osmotic laxatives and stimulant cathartics are the drugs of the first choice by the patients to treat constipation. OTC products have shown good results in patients taking opioid analgesics for less than 4 weeks.
In addition, lockdown restrictions and the need to maintain social distancing due to the ongoing COVID-19 pandemic have resulted in more number of people staying at home. Hence, a sedentary lifestyle has resulted in the development of opioid induced constipation. In addition, irrational intake of OTC drugs and lack of physical activity will further aggravate the occurrence of opioid induced constipation in the elderly population
Key questions answered in this report
- What are the key micro and macro environmental factors that are impacting the growth of Opioid Induced Constipation Drugs market?
- What are the key investment pockets with respect to product segments and geographies currently and during the forecast period?
- Estimated forecast and market projections up to 2030.
- Which segment accounts for the fastest CAGR during the forecast period?
- Which market segment holds a larger market share and why?
- Are low and middle-income economies investing in the Opioid Induced Constipation Drugs market?
- Which is the largest regional market for Opioid Induced Constipation Drugs market?
- What are the market trends and dynamics in emerging markets such as Asia Pacific, Latin America, and Middle East - Africa?
- Which are the key trends driving Opioid Induced Constipation Drugs market growth?
- Who are the key competitors and what are their key strategies to enhance their market presence in the Opioid Induced Constipation Drugs market worldwide?
Key Topics Covered:
1. Preface
2. Executive Summary
3. Opioid Induced Constipation Drugs Market: Business Outlook & Market Dynamics
3.1. Introduction
3.2. Global Opioid Induced Constipation Drugs Market Value, 2020 - 2030, (US$ Million)
3.3. Market Dynamics
3.3.1. Market Drivers
3.3.2. Market Restraints
3.3.3. Key Challenges
3.3.4. Key Opportunities
3.4. Impact Analysis of Drivers and Restraints
3.5. See-Saw Analysis
3.6. Porter's Five Force Model
3.7. PESTEL Analysis
3.8. Heptalysis Analysis
3.9. Critical Investigation of Business Problems Through Five Whys Root Cause Analysis & Relevant Solutions
4. Opioid Induced Constipation Drugs Market: By Drug Type, 2020-2030, USD (Million)
5. Opioid Induced Constipation Drugs Market: By Prescription Type, 2020-2030, USD (Million)
6. North America Opioid Induced Constipation Drugs Market, 2020-2030, USD (Million)
7. UK and European Union Opioid Induced Constipation Drugs Market, 2020-2030, USD (Million)
8. Asia Pacific Opioid Induced Constipation Drugs Market, 2020-2030, USD (Million)
9. Latin America Opioid Induced Constipation Drugs Market, 2020-2030, USD (Million)
10. Middle East and Africa Opioid Induced Constipation Drugs Market, 2020-2030, USD (Million)
11. Company Profile
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