EMERYVILLE, Calif.--(BUSINESS WIRE)--Metagenomi, a gene editing company with a versatile portfolio of next-generation CRISPR tools, announced today that it will present a poster at the Cold Spring Harbor Laboratory’s Genome Engineering: CRISPR Frontiers conference, which will be held virtually August 18-20, 2021.
The poster describes Metagenomi’s newly discovered CRISPR-associated transposase (CAST) systems, which allow for targetable integration of large DNA fragments into genomes. These systems have the potential to overcome limitations of current approaches that could be used to replace defective, disease-causing genes. Metagenomi’s scientists extensively mined environmental metagenomics datasets to identify these systems and showed that they are active in E. coli. This work is based on Metagenomi’s proprietary high-throughput screening methodologies and leverages the newly discovered collection of CASTs in order to streamline these multi-component systems. These advancements will enable further development for in vivo and ex vivo gene editing applications.
Details of the poster are below:
Title: Engineered CRISPR-associated Transposases with Minimized Components
Presenting Author: Jason Liu, Ph.D.
Session Time: Poster will be available at 9:30 a.m. ET, August 18, 2021
About Metagenomi
Metagenomi is a gene editing company committed to developing potentially curative therapeutics by leveraging a proprietary toolbox of next-generation gene editing systems to accurately edit DNA where current technologies cannot. Our metagenomics-powered discovery platform and analytical expertise reveal novel cellular machinery sourced from otherwise unknown organisms. We adapt and forge these naturally evolved systems into powerful therapeutic tools that can be leveraged by partners and fuel our own pipeline of novel medicines. Our goal is to revolutionize gene editing for the benefit of patients around the world. For more information, please visit https://metagenomi.co/.
