FRANKFURT--(BUSINESS WIRE)--A new single-use fermentor matches the performance of stainless steel while eliminating clean/steam-in-place steps, reducing set-up time and mitigating cross-contamination risk in microbial fermentation.
The Thermo Scientific HyPerforma Single-Use Fermentor (S.U.F.) is the first single-use system specifically engineered for microbial fermentation and designed to support scale up from the lab to GMP production. Capable of meeting the aggressive performance demands of industrial microbiology, the HyPerforma S.U.F. integrates into existing Thermo Scientific single-use technologies to achieve exceptional efficiency and scalability across the entire bioprocessing workflow.
Thermo Fisher will showcase its new HyPerforma Single-Use Fermentor this week at ACHEMA 2015, June 15-19 at the exhibition grounds of Messe Frankfurt, Frankfurt am Main, Germany, Laboratory and Analytical Techniques Hall 4.2, Booth D8 and in the Thermal Processes Hall 5.1.
“Until now, fermentation equipment has been hard to convert to single-use due to the aggressive demands of fast-growing microbial cultures. Modified single-use bioreactors have been used, but are not designed for ideal growth conditions,” said Daniel Nelson, product manager, single-use systems at Thermo Fisher Scientific. “Through engineering an innovative, single-use exhaust and condenser system, coupled with powerful mixing, we overcame constraints in oxygen transfer to create the first purpose-built single-use fermentor. The HyPerforma S.U.F. is a natural progression developed specifically for fermentation processes and a dedicated tool needed to increase choice, flexibility and performance for all bioprocessing workflows.”
Key product features include:
- Effective mass transfer, powerful mixing, and temperature control using three Rushton-style impellers and baffled, jacketed vessel.
- 5:1 turndown ratio and 3:1 height-to-diameter ratio for consistent scalability and flexibility of process design (both 30L and 300L models).
- Efficient exhaust management system, enabling high flow rates (2VVM).
- Vertical access door for easy loading and retrieval of the BioProcess Containers and harvest lines.
- Turn-around times between batches as low as two hours.
As a two-part product, the HyPerforma S.U.F. comes paired with a Thermo Scientific BioProcess Container (BPC) – pre-sterilized and gamma irradiated. With an open architecture design, the HyPerforma SUF with BPC is highly flexible. It can also be retrofitted into existing fermentor operations, as well as configured to operate with existing software and control equipment, or delivered turnkey for immediate use.
For more information on the HyPerforma S.U.F., please visit our website at www.thermoscientific.com.
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