DUBLIN--(BUSINESS WIRE)--Research and Markets (http://www.researchandmarkets.com/research/lb9n2k/protein_kinase) has announced the addition of the "Protein Kinase Inhibitors in Oncology Drug Pipeline Update 2013" report to their offering.
Protein kinase inhibitors such as Gleevec, Iressa and Tarceva have allowed the biotechnology industry to deliver on the promise of targeted cancer drugs. However, these three successful drugs are just the top of an emerging line of therapy. Given the fact that they all target tyrosine kinases and that kinase mutations can cause patients to become resistant to these drugs, there is plenty of room for more competition.
There are today 305 companies plus partners developing 615 PKI drugs in 2089 developmental projects in cancer. In addition, there are 8 suspended drugs and the accumulated number of ceased drugs over the last years amount to another 332 drugs. Protein Kinase Inhibitors In Oncology Drug Pipeline Update lists all drugs and gives you a progress analysis on each one of them. Identified drugs are linked to 237 different targets. All included targets have been cross-referenced for the presence of mutations associated with human cancer. To date 230 out of the 235 studied drug targets so far have been recorded with somatic mutations. The software application lets you narrow in on these mutations and links out to the mutational analysis for each of the drug targets for detailed information. All drugs targets are further categorized on in the software application by 45 classifications of molecular function and with pathway referrals to BioCarta, KEGG, NCI-Nature and NetPath.
Drug Pipeline Update at a Glance
Investigators
Includes more than 305 principal companies plus their collaborators. There is direct access from inside the application to web pages of all principal companies.
Biological Structures
The identity of available biological structures on 178 drug targets was retrieved from the RCSB Protein Databank for you to easily review the 3014 structures available today among drug targets.
For more information visit http://www.researchandmarkets.com/research/lb9n2k/protein_kinase
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