DUBLIN--(BUSINESS WIRE)--Research and Markets(http://www.researchandmarkets.com/research/b648aa/myelodysplastic_sy) has announced the addition of the "Myelodysplastic Syndromes: Pathobiology and Clinical Management, Second Edition" book to their offering.
Written by a team of leading authorities in pathogenesis, diagnostic techniques, and clinical management strategies in myelodysplastic syndrome (MDS), this text provides a concise, easy-to-follow review of the advances in the science, classification, diagnosis, and management of the condition. This Second Edition features:
- A new eight-page color insert
- 200 color and black-and-white illustrations
- Reworked content organized into three sections: MDS epidemiology and biology; diagnosis, classification, and prognosis; and MDS therapy
- Thoroughly updated chapters reflecting a shift from the topical focus as dictated by the evolution of the field
New topics in Myelodysplastic Syndrome include:
- Del(5q) and 5q-syndrome, CMML, and MDS-MPD overlap syndrome
- The reborn DNA methyltransferase inhibiting nucleoside analogs
- The diagnosis of chronic myelomonocytic leukemia and other MDS cases with myeloproliferative features
- The role of mitochondria and the potential importance of iron overload in MDS
- Global genomics approaches, such as cDNA expression arrays, array-based comparative genomic hybridization, and single nucleotide polymorphism array
- The role of abnormal mitochondrial ferritin accumulation and other mitochondrial metabolic anomalies in MD
- Other disease-associated alterations, such as abnormalities of B lymphocyte populations in MD
- Three recently approved drugs: azacitidine, lenalidomide, and decitabine
Key Topics Covered:
- Myelodysplastic Syndrome: Historical Aspects and Classification.
- Epidemiology of MDS.
- Cytogenetics & Molecular Biology of MDS.
- Global Genomic Approaches to MDS.
- The Role of Apoptosis in MDS.
- The Role of Mitochondria in MDS.
- Defects in Iron Metabolism and Iron Overload in MDS.
- Therapy-Related MDS and Myeloid Leukemia.
- Diagnosis of MDS: Criteria and Challenges.
- Hypocellular MDS and Hypocellulcar Acute Myeloid Leukemias: Relationship to Aplastic Anemia.
- Diagnostic Utility of Flow Cytometry.
- Deletion 5q and 5q-Syndrome in MDS.
- CMML and MDS-MPD Overlap Syndromes.
- MDS in Children.
- Prognostic Factors in the Assessment of Patients with MDS.
- Therapeutic Strategies: The Approsch to Care of Patients w/ MDS, and Criteria for Response.
- Management of Cytopenias in MDS.
- Immune Dysregulation And The Role For Immunotherapy in Myelodysplastic Syndrome (MDS).
- Lenalidomide Therapy in MDS.
- DNA Methyltransferase Inhibitor Therapy in MDS.
- Intensive Chemotherapy and Stem Cell Transplantation in MDS.
For more information visit http://www.researchandmarkets.com/research/b648aa/myelodysplastic_sy