DUBLIN--(BUSINESS WIRE)--Research and Markets (http://www.researchandmarkets.com/research/35aa25/francisella_tulare) has announced the addition of John Wiley and Sons Ltd's new book "Francisella Tularensis: Biology, Pathogenicity, Epidemiology, and Biodefense" to their offering.
This is the first book on tularemia. With the biodefense initiative, there has been a major boost by the NIH to fund studies on bioterrorism agents, including Francisella, which is classified as a class A bioterrorism agent. With the major interest in biodefense and the major threats of bioterrorism, Francisella tularensis has become a major interest for microbiologists, cell biologists, immunologists, and infectious disease experts.
The volume explores the mechanisms of pathogenesis, genetics and genetic manipulations, genomics and metagenomics, identification of vaccine candidates, animal models to study the disease process, mechanisms of protective immunity, pathophysiology, vaccine development, genetic susceptibility, more effective therapies, clinical diagnosis, and routine and rapid microbiological diagnostic tools.
Key Topics Covered:
Preface
1. Tularemia: History, Epidemiology, Pathogen Physiology, and Clinical Manifestations: Anders Sjostedt
2. Molecular Ecology, Epidemiology and Evolution of Francisella: Paul Keim, Anders Johannson, and David Wagner
3. Genetics and Genetic Manipulations in Francisella Tularensis: Tom Zahrt and Dara Frank
4. Francisella Tularensis: Genomics and Proteomics: Richard Titball and Joseph Petrosino
5. The Francisella Pathogenicity Island: Francis E. Nano and Crystal Schmerk
6. Molecular and Genetic Bases of Pathogenesis in Francisella Tularensis: Jeffrey R. Barker and Karl E. Klose
7. Uptake and Intracellular Fate of Francisella Tularensis in Human Macrophages: Daniel Clemens and Marcus A. Horwitz
8. Type II Secretion and Type IV Pili of Francisella: Tina Guina and Ake Forsberg
9. The Structure and Function of Francisella LPS: John Gunn and Robert Ernst
10. Francisella Tularensis Activation of the Inflammasome: David S. Weiss, Thomas Henry, and Denise M. Monack
11. Animal Models of Francisella Tularensis Infection: C. Rick Lyons and Terry Wu
12. Mucosal Immunopathogenesis of Francisella Tularensis: Dennis W. Metzger, Chandra Shekhar Bakshi, and Girish Kirimanjeswara
13. Innate and Adaptive Immunity to Francisella: Karen L. Elkins, Siobhn C. Cowley, and Catharine M. Bosio
14. Vaccines against Francisella Tularensis: J. Wayne Conlan and Petra C.F. Oyston
15. Pneumonic Tularemia on Martha's Vineyard: Clinical, Epidemiologic and Ecological Characteristics: Bela T. Matyas, Henry S. Nieder, Sam R. Telford III
16. New Approaches to Diagnosis and Therapy of Tularemia: Arne Trnvik and May Chu
17. Biosafety and Selectable Markers: Richard W. Titball, Anders Sjostedt, Martin S. Pavelka Jr., and Francis Nano
Index of Contributors
For more information visit http://www.researchandmarkets.com/research/35aa25/francisella_tulare